2021-02-15

2, AGAP2-AS1 (AGAP2 Antisense RNA 1), miR-16-5p, ANXA11, 31088485. 3, AK054386, miR-199, None specified, 31827704. 4, ANRIL (CDKN2B antisense

HGNC ID. HGNC: 27 Mar 2020 LncRNA AGAP2-AS1 (AGAP2 Antisense 1), which is also known as PUNISHER ENSG00000255737, is located at 12q14.1 and has been 2021年3月2日 Introduction: It has been reported that lncRNA AGAP2-AS1 promotes the development of gastric cancer, lung cancer and breast cancer. 18 Feb 2021 However, the role and mechanism of AGAP2-AS1 in papillary thyroid carcinoma ( PTC) remain unclear. Thus, in this study, we aimed to explore Moreover, lncRNA AGAP2-AS1 promotes cell proliferation and invasion in gastric cancer [13]. How- ever, the expression and its function roles of lncRNA. AGAP2- 25 Sep 2020 The current study aimed to elucidate the role of lncRNA AGAP2-AS1/miR-195-5p/ PDZ and LIM domain 5 (PDLIM5) in prostate cancer 5 Mar 2021 AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include 18 Sep 2020 The lncRNA AGAP2 antisense RNA 1 (AGAP2-AS1) is Keywords: LncRNA, AGAP2-AS1, papillary thyroid cancer, miR-424-5p, MMP2. with three genes (CTBP1-AS2, OTUD6B-AS1, and AGAP2-AS1) exceeding the study-wide Bonferroni- corrected P-value (PBonf < 0.0023, Pcombined ¼ 1.1 Â OTUD6B-AS1 and AGAP2-AS1) exceeding the study-wide Bonferroni-corrected ρ-value.

Agap2-as1

1. The AGAP2-AS1 mRNA classified 23 out of 24 samples correctly, without the need for a larger gene panel. The trend of expression was confirmed with RT-PCR.The correlation between sample status as either progressor or non-progressor and AGAP2-AS1 level was R 2 =0.69, p<0.01. AGAP2‑AS1 were highly expressed in renal tissues. The expression of AGAP2 -AS1 was detected in 539 ccRCC tissues and 72 adjacent healthy tissues using Wilcoxon rank sum test. AGAP2-AS1 demonstrated higher expression in tumor tissues compared with normal tissues (P<0.001; Fig. 1A).

Mechanistically, AGAP2-AS1 inhibited cell metastasis and proliferation by AGAP2-AS1, which is transcribed from a gene located on 12q14.1 and is 1567 nt in length, has been found to be overexpressed in human cancers. In non-small cell lung cancer (NSCLC), an increased expression of AGAP2-AS1 regulated the transcription of downstream targets by interacting with epigenetic proteins [ 13 ]. Besides, lncRNA AGAP2-AS1 could bind to miR-195-5p which targeted PDLIM5 and subsequently downregulated its expression, ultimately impeding the progression of prostate cancer.

AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets. Click the + buttons to view associations for AGAP2-AS1 from the datasets below. If available, associations are ranked by standardized value

FGFR1 was targeted by miR-497 in CRC cells Furthermore, dual luciferase reporter assay showed that overexpression of AGAP2-AS1 blocked the inhibition AGAP2-AS1 promotes CCA cell proliferation in vitroandvivo.(A-B)CCK-8 assay was performed to determine the proliferation of HUCCT1 and RBE cells with si … Interestingly, AGAP2‐AS1 sponges miR‐4,668‐3p to release SRSF1 in CRC. Furthermore, in the rescue functional assay, miR‐4,668‐3p down‐regulation exacerbated the malignant behaviors of AGAP2‐AS1‐depleted CRC cells, whereas such effects were further … SP1-induced lncRNA AGAP2-AS1 expression promotes chemoresistance of breast cancer by epigenetic regulation of MyD88 Symbol: AGAP2-AS1: Name: AGAP2 antisense RNA 1: Type: other: Synonyms: AGAP2 antisense RNA 1, AGAP2-AS1, LOC100130776, PNS, PUNISHER: Species: Human (AGAP2-AS1 EG The gene AGAP2-AS1 may have Genomic and Proteomic products available from Sigma-Aldrich. 2020-06-05 Complete information for SATB2-AS1 gene (RNA Gene), SATB2 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium AGAP2-AS1 promoted glioma cell proliferation by sponging miR-15a/b-5p to upregulate the expression of HDGF; AGAP2-AS1 was upregulated and transcriptionally induced by SP1 in breast cancer..ChIP assays showed that AGAP2-AS1-bound CBP increased the enrichment of H3K27ac at the promoter region of MyD88, thus resulting in the upregulation of MyD88.

AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include Glioblastoma and High Grade Glioma. Additional gene information for AGAP2-AS1 Gene HGNC (48633)

Your search resulted in multiple matches. Please select a position: Gencode Genes AGAP2-AS1 (ENST00000542466.2) at chr12:57726271-57728356 - Homo sapiens AGAP2 antisense RNA 1 (AGAP2-AS1), long non-coding RNA. 3 Dec 2020 Clinically, increased expression of serum AGAP2-AS1 predicts poor response to trastuzumab treatment in breast cancer patients. In conclusion, 2 Mar 2021 LncRNA AGAP2-AS1 Promotes Cancer Cell Proliferation, Migration and Invasion in Colon Cancer by Forming a Negative Feedback Loop with 2 Mar 2021 LncRNA AGAP2-AS1 Promotes Cancer Cell Proliferation, Migration and Invasion in Colon Cancer by Forming a Negative Feedback Loop with HGNC data for AGAP2-AS1.

Jérôme M. Rousseau - Responsable de département - agap2 agap2 - Agap2 Agap2-as1. Agap2 Gene · Agap2 Switzerland · Agap2it · Agap2-as1 · Agap2 Netherlands · Agap2 Avis · Agap2 Deutschland · Agap2 Glassdoor · Operation Hydra Case · Srijit Gumamit ng mga kamangha-manghang mga nakasisiglang larawan para sa iyong blog, tumblr, website, portfolio, o anumang pipiliin mong ibahagi. Stunning AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include Glioblastoma and High Grade Glioma. Additional gene information for AGAP2-AS1 Gene HGNC (48633) Results: AGAP2-AS1 was upregulated and transcriptionally induced by SP1 in breast cancer. Overexpression of AGAP2-AS1 promoted cell growth, suppressed apoptosis, and caused trastuzumab resistance, whereas knockdown of AGAP2-AS1 showed an opposite effect. Recently, the lncRNA AGAP2-AS1 was identified as an oncogenic lncRNA in human non-small cell lung cancer (NSCLC) and its elevated expression was linked to NSCLC development and progression.
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Furthermore, knockdown of AGAP2-AS1 significantly inhibited GC cell proliferation, migration, and … AGAP2-AS1 was upregulated in MSC-cultured cells, and knockdown of AGAP2-AS1 reversed the MSC-mediated trastuzumab resistance. Furthermore, MSC culture … 2017-02-16 2019-05-14 2017-02-16 AGAP2-AS1 is Upregulated in NSCLC Tissues To determine whether AGAP2-AS1 is involved in NSCLC tumorigenesis, We determined the ex-pression levels of AGAP2-AS1 in NSCLC tissues and matched normal lung tissues by RT-qPCR.

To explore the functional relevance of AGAP2AS1 in - GBM cells, we interfered endogenous AGAP2-AS1 expression in U87/MG and U251/MG cells by We also found that AGAP2-AS1 promoted colon cancer cell proliferation, migration and invasion through the Hippo signaling.
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Long non-coding RNA (lncRNA) AGAP2-AS1 acts as an oncogene in several types of cancers. However, the role and mechanism of AGAP2-AS1 in papillary thyroid carcinoma (PTC) remain unclear. Thus, in this study, we aimed to explore the role of AGAP2-AS1 in PTC. Our results showed that AGAP2-AS1 was signi …

Additionally, the expression of AGAP2-AS1 was analyzed Prostate cancer remains a significant cause of cancer-related deaths in male population. More recently, accumulating evidence continues to implicate long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and mRNAs in various types of cancers, including prostate cancer. The current study aimed to elucidate the role of lncRNA AGAP2-AS1/miR-195-5p/PDZ and LIM domain 5 (PDLIM5) in prostate cancer 2018-08-29 · AGAP2-AS1 was upregulated and transcriptionally induced by SP1 in breast cancer. Overexpression of AGAP2-AS1 promoted cell growth, suppressed apoptosis, and caused trastuzumab resistance, whereas knockdown of AGAP2-AS1 showed an opposite effect.